Loading...
Free shipping on orders $50 or more
All ink & toner come with a one-year 100% satisfaction guarantee.
Our products will never void your printer's warranty.

Replacement HP DeskJet Plus 4121 Ink Cartridges from $18.95

  • MOST POPULAR
    High Yield HP 67 XL Ink Cartridges 2-Pack: 1 Black & 1 Tri-color
    Retail Price: $52.98
    $35.90
    Save $17.08 (32% off retail price)
  • HP Printer Ink 67 Cartridges Combo Pack of 2: 1 Black and 1 Tri-color
    Retail Price: $40.90
    $35.90
    Save $5.00 (12% off retail price)
  • High Yield HP Printer Ink 67XL Combo Pack of 3: 2 Black and 1 Tri-color
    Retail Price: $78.97
    $50.97
    Eligible for free shipping
    Save $28.00 (35% off retail price)
  • HP 67 Ink Cartridges 3-Pack: 2 Black, 1 Tri-color
    Retail Price: $59.90
    $50.97
    Eligible for free shipping
    Save $8.93 (15% off retail price)
  • High Yield HP Ink 67 XL Cartridges Combo Pack of 5: 3 Black and 2 Tri-color
    Retail Price: $131.95
    $82.45
    Eligible for free shipping
    Save $49.50 (38% off retail price)
  • Cheap HP 67 Ink Cartridges 5-Pack: 3 Black and 2 Tri-color
    Retail Price: $95.90
    $82.45
    Eligible for free shipping
    Save $13.45 (14% off retail price)
  • HP 67 Ink Cartridge Black, Single Pack
    Retail Price: $28.00
    $18.95
    Save $9.05 (32% off retail price)
  • High Yield HP 67XL Ink Cartridge Black, Single Pack
    Retail Price: $25.99
    $18.95
    Save $7.04 (27% off retail price)
  • HP 67XL Color Ink Cartridge, Single Pack
    Retail Price: $26.99
    $19.95
    Save $7.04 (26% off retail price)
  • HP Ink 67 Color Cartridge, Single Pack
    Retail Price: $21.00
    $19.95
    Save $1.05 (5% off retail price)

HP DeskJet Plus 4121 Ink Replacement Guide

  1. Make sure that the printer is turned on.
  2. Open the printer's ink cartridge access door, which can be found in front of the printer.
  3. The ink cartridge's carriage will automatically move, so make sure to wait for it to completely stop moving before you proceed.
  4. Gently push the ink cartridge down to release it, then pull it out from the printer.
  5. Get your new CompAndSave HP 4121 ink cartridge. Open it over a sink or garbage can to avoid any messes in case it leaks, as sometimes factories tend to overfill ink cartridges. Make sure to touch only the black plastic part, then remove the covering tape that is usually bright in color, as well as the plastic protective case, if there is one, before installing it.
  6. Insert the new ink cartridge to its respective slot until it snaps lock into place.
  7. Close the printer's ink cartridge access door.

HP DeskJet Plus 4121 Ink Cartridges FAQ

How do I know which ink cartridge to buy for an HP printer?

To know the ink cartridge intended for your printer, you may check the printer's manual or check the last or existing cartridge installed in your printer. On the front should be a label or sticker with the model number. For example, the HP DeskJet 4121 printer uses the standard-yield HP 67 and the high-yield HP 67XL ink cartridges. For more information, you may also check our find my ink guide, and you will be redirected to the right page.

Can you use another number of ink cartridges in an HP printer?

No, you can't. Each HP printer has a designated ink cartridge for it. These cartridges have different sizes, yields, and compatibility, and your printer will not recognize the cartridge if it's the wrong one. Using the wrong ink cartridge on your HP printer might cause some issues. To know the model number of the cartridge your printer is using, you may check the user's manual that came with your printer. You may also check the existing cartridge that is installed in your printer; on the front or side is a label or sticker with the model number, which usually consists of alphanumeric characters. For example, the HP DeskJet 4121 printer uses an ink cartridge that has the model code HP 67 for standard yield and HP 67XL for high yield.

Replacement HP DeskJet Plus 4121 Ink Cartridges Reviews

295 Customer Reviews
4.6 out of 5 stars
Sort by
Rating
Newest
Helpfulness
  • Review for Replacement HP 67XL Ink Cartridge Black - 3YM57AN - High Yield
    Oct 23, 2026
    Verified Buyer
    Worked without any problems.
    Was this review helpful?
  • Gets the job done
    Review for Replacement HP Ink 67 XL Cartridges Combo Pack of 5 - High Yield: 3 Black & 2 Tri-color
    Oct 6, 2026
    Verified Buyer
    Fits my printer perfectly and the price is right. Fast shipping.
    Was this review helpful?
  • Excellent products. Works great!
    Review for Replacement HP Printer Ink 67XL Cartridges Combo Pack of 3 - High Yield: 2 Black & 1 Tri-color
    Oct 2, 2026
    Verified Buyer
    Excellent products. Works great!
    Was this review helpful?
  • N/A
    Review for Replacement HP 67 XL Ink Cartridges 2-Pack - High Yield: 1 Black & 1 Tri-color
    Oct 1, 2026
    Verified Buyer
    N/A
    Was this review helpful?
  • Review for Replacement HP Printer Ink 67 Cartridges Combo Pack of 2 - 1 Black & 1 Tri-color
    Sep 29, 2026
    Verified Buyer
    Good job. Thank you
    Was this review helpful?
  • Worked great.
    Review for Replacement HP 67XL Ink Cartridge Black - 3YM57AN - High Yield
    Sep 24, 2026
    Verified Buyer
    Worked great.
    Was this review helpful?
  • Review for Replacement HP Printer Ink 67 Cartridges Combo Pack of 2 - 1 Black & 1 Tri-color
    Jul 20, 2026
    Verified Buyer
    Product works great and installs easily.
    Was this review helpful?
  • Review for Replacement HP 67 XL Ink Cartridges 2-Pack - High Yield: 1 Black & 1 Tri-color
    Jul 19, 2026
    Verified Buyer
    Excellent Products
    Was this review helpful?
  • Have not had to install new ink quite yet.
    Review for Replacement HP Printer Ink 67 Cartridges Combo Pack of 2 - 1 Black & 1 Tri-color
    Jul 7, 2026
    Verified Buyer
    It was delivered so much earlier than expected. Thank you!
    Was this review helpful?
  • Review for Replacement HP 67XL Ink Cartridge Black - 3YM57AN - High Yield
    Jul 1, 2026
    Verified Buyer
    Very good quality
    Was this review helpful?